Never before in British legal history has such a highly respected group of medical experts come together to challenge the evidence against a convicted serial killer.
The 14 neonatologists who have reviewed the Lucy Letby data are world-class specialists, with thousands of medical and scientific papers published between them.
Their conclusion: there were no murders, only the precariousness of prematurity, coupled with the tragic incompetence of a failing baby unit at the Countess of Chester Hospital.
"If this was a hospital in Canada, it would be shut down," was the damning conclusion of Dr Shoo Lee, an eminent Canadian neonatologist, and head of the division of neonatology at the University of Toronto.
At a press conference in central London, the major review found doctors at the Countess of Chester had misdiagnosed diseases, cared for infants beyond their capabilities, demonstrated poor skills, and did not know how to use equipment.
These, remember, were the very doctors who took the stand to point the finger at Letby. In some instances, they even helped the police gather evidence against the nurse.
According to the new review, in the case of one baby, doctors missed a lethal bacterial infection called Setenotrophomonas maltophilia, and so failed to give life-saving antibiotics.
"This was a preventable death," Dr Lee told a room packed with reporters and television crews.
Another baby died after getting a blood clot when doctors left empty infusion lines in the body for several hours. When the infusion was finally switched on, the clot dislodged and travelled to the brainstem, triggering a sudden collapse.
In the case of Baby K, Letby was convicted of attempting to murder the infant by dislodging her breathing tube. But Dr Lee said the tube was never inserted correctly by a doctor in the first place.
"The consultant did not understand the basics of resuscitation, air leak and mechanical ventilation," he said.
'I've never known anything like it'
In a mammoth two-hour press conference broadcast across the world, Dr Lee went through case after case demolishing the prosecution's assertion that any babies had been murdered at the Countess of Chester.
Mark McDonald, Letby's new barrister, rightly described the presentation as a game-changer.
"I've never known anything like it," he said. "I mean it's a grand statement to make - but never before have we had such an experienced credible body of experts come together across the world and say something has gone wrong."
Certainly, the dial seems to be shifting. The Criminal Cases Review Commission (CCRC) set up a team weeks ago to begin "preliminary reading and familiarisation" and on Tuesday received an application from Letby's legal team.
The CCRC said that "work has begun to assess the application" and it would be astonishing if it did not refer the case back to appeal based on the weight of the new evidence.
While it is impossible to say that Letby is innocent, there is overwhelming data showing that there are plausible alternative explanations for the deaths and collapses of the babies in her care.
The spike in mortality at the Countess of Chester came at a time when the NHS was besieged with maternity scandals, and it may turn out that this was another. It is arguably more likely than a serial killer stalking the wards, particularly given the known problems on the unit.
Letby's defence team pointed out dozens of problems at the hospital, including inadequate staffing, poor plumbing and drainage that placed babies at risk of infection, IV drugs being prepared in corridors, and transfer delays.
"The medical evidence doesn't support murder in any of these babies," Dr Lee concluded. "Just natural causes and bad medical care."
Dr Lee became involved in the case after a paper he co-authored in 1989 was cited in Letby's trial by the prosecution as proof that several of the babies had died through air being injected into a vein.
However, the neonatologist said it showed nothing of the kind.
"If that was true, it would be the first case ever described," he said. The expert could have nipped the case in the bud, but he was never contacted by Cheshire Police or the Crown Prosecution Service.
What is clear is that the Thirwall Inquiry must now be paused. The blinkered probe has ploughed on attempting to find out how Letby could have been stopped despite the mounting doubts about her guilt.
Lady Justice Thirwall even dismissed the genuine concerns as "noise" that caused "enormous stress" for the victims' families.
The families must not be forgotten in all this, but many people have had their lives destroyed by the events over the past 10 years.
Perhaps it is now the NHS and the justice system that should be on trial.
If there were cracks in the case against Lucy Letby before today, there are now gaping holes.